Journal of Yeungnam Medical Science

Wan Seok Seo

10 Articles

An update on the cause and treatment of sleep disturbance in children and adolescents with autism spectrum disorder: Wan Seok Seo; Yeungnam Univ J Med. 2021;38(4):275-281. Published online September 13, 2021; DOI: https://doi.org/10.12701/yujm.2021.01410

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Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by abnormalities in social communication/interaction and restrictive, repetitive patterns of behavior. ASD is a relatively common psychiatric disorder, with a prevalence of approximately 1.7% in children. Although many children and adolescents with ASD visit the hospital for medical help for emotional and behavioral problems such as mood instability and self-harming behavior, there are also many visits for sleep disturbances such as insomnia and sleep resistance. Sleep disturbances are likely to increase fatigue and daytime sleepiness, impaired concentration, negatively impact on daytime functioning, and pose challenges in controlling anger and aggressive behavior. Sleep disturbance in children and adolescents with ASD negatively affects the quality of life, nothing to say the quality of life of their families and school members. In this review, sleep disturbances that are common in children and adolescents with ASD and adolescents are presented. The developmental and behavioral impacts of sleep disturbances in ASD were also considered. Finally, non-pharmacological and pharmacological treatments for sleep disturbances in children and adolescents with ASD and adolescents are reviewed.

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Current Pharmacological Treatment for Sleep Disorders in Children and Adolescents with Autism Spectrum Disorder
Hatice Altun, Semiha Cömertoğlu Arslan
European Journal of Therapeutics.2024;[Epub] CrossRef
Sleep and Autism Spectrum Disorder: A Comprehensive Review of Diagnosis, Markers, Interventions, and Treatments
Deepa Burman, Karthikeyan Ramanujam, Dilshad Manzar, Vijay Kumar Chattu, David Warren Spence, Nevin F. W. Zaki, Haitham Jahrami, Seithikurippu R. Pandi-Perumal
Sleep and Vigilance.2023; 7(1): 9. CrossRef
Efficacy of Melatonin for Insomnia in Children with Autism Spectrum Disorder: A Meta-analysis
Mei Xiong, Fang Li, Zhaohua Liu, Xin Xie, Hongli Shen, Weiteng Li, Liping Wei, Rongfang He
Neuropediatrics.2023; 54(03): 167. CrossRef
Sleep disturbances and emotional dysregulation in young children with autism spectrum, intellectual disability, or global developmental delay
Irene Favole, Chiara Davico, Daniele Marcotulli, Roberta Sodero, Barbara Svevi, Federico Amianto, Federica S. Ricci, G. Maurizio Arduino, Benedetto Vitiello
Sleep Medicine.2023; 105: 45. CrossRef
Where I am from matters: factors influencing behavioral and emotional changes in autistic individuals during COVID-19 in Latin America
María Cecilia Montenegro, Ana C. Ramírez, Juventino Hernandez Rodriguez, Bianca T. Villalobos, Gabriela Garrido, Cecilia Amigo, Daniel Valdez, Natalia Barrios, Sebastián Cukier, Alexia Rattazzi, Analía Rosoli, Ricardo García, Cristiane S. Paula, Georgina
Frontiers in Psychiatry.2023;[Epub] CrossRef
A novel case of prolonged Ifosfamide encephalopathy and long-term treatment with methylene blue: a case report and review of literature
Gabriel Chain, Mudit Kalia, Karen Kestenbaum, Lara Pappas, Anna Sechser-Perl, Gadi Abebe Campino, Nibal Zaghloul
BMC Pediatrics.2022;[Epub] CrossRef
Sleep Disturbances in Children Affected by Autism Spectrum Disorder
Jessica Galli, Erika Loi, Lucrezia Maria Visconti, Paola Mattei, Anna Eusebi, Stefano Calza, Elisa Fazzi
Frontiers in Psychiatry.2022;[Epub] CrossRef
Analysis of sleep problem in children aged 1–3 years with autism spectrum disorder in Zhejiang province, China
Dan Yao, Shasha Wang, Fangfang Li, Minjie Gao, Jie Shao
Frontiers in Psychiatry.2022;[Epub] CrossRef
Understanding sleep and sleep disturbances in autism spectrum disorder, and management of insomnia: an update
Hye-Geum Kim
Yeungnam University Journal of Medicine.2021; 38(4): 265. CrossRef

Yeungnam University type drive-through (YU-Thru) coronavirus disease 2019 (COVID-19) screening system: a rapid and safe screening system: Wan Seok Seo, Seong Ho Kim, Si Youn Song, Jian Hur, Jun Lee, Sunho Choi, Yoojung Lee, Dai Seg Bai; Yeungnam Univ J Med. 2020;37(4):349-355. Published online September 18, 2020; DOI: https://doi.org/10.12701/yujm.2020.00640

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Abstract PDF

Active and prompt scale-up screening tests are essential to efficiently control the coronavirus disease 2019 (COVID-19) outbreak. The goal of this work was to identify shortcomings in the conventional screening system (CSS) implemented in the beginning of the outbreak. To overcome these shortcomings, we then introduced a novel, independently developed system called the Yeungnam University type drive-through (YU-Thru), and distributed it nationwide in Korea. This system is similar to the drive-throughs utilized by fast food restaurants. YU-Thru system has shortened the time taken to test a single person to 2–4 minutes, by completely eliminating the time required to clean and ventilate the specimen collection room. This time requirement was a major drawback of the CSS. YU-Thru system also reduced the risk of subjects and medical staff infecting one another by using a separate and closed examination system. On average, 50 to 60 tests were conducted per day when using the CSS, while now up to 350 tests per day are conducted with the YU-Thru system. We believe that the YU-Thru system has made an important contribution to the rapid detection of COVID-19 in Daegu, South Korea. Here, we will describe the YU-Thru system in detail so that other countries experiencing COVID-19 outbreaks can take advantage of this system.

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Experience of operating a medical humanities course at one medical school during the COVID-19: a retrospective study
Yu Ra Kim, Hye-won Shin, Young Hwan Lee, Seong-Yong Kim
Journal of Yeungnam Medical Science.2023; 40(2): 179. CrossRef
Lessons Learned From an Analysis of the Emergency Medical Services’ COVID-19 Drive-Through Testing Facilities in Israel
Itay Zmora, Evan Avraham Alpert, Uri Shacham, Nisim Mishraki, Eli Jaffe
Disaster Medicine and Public Health Preparedness.2022; 16(5): 2091. CrossRef
A study on the mental health of students at a medical school during COVID-19 outbreak: a retrospective study
Yu Ra Kim, Hye Jin Park, Bon-Hoon Koo, Ji Young Hwang, Young Hwan Lee
Journal of Yeungnam Medical Science.2022; 39(4): 314. CrossRef

Manifestation of Cognitive Function in Geriatric Patient with Subjective Memory Complaint.: Han Kyul Park, Jin Sung Kim, Jong Bum Lee, Wan Seok Seo, Bon Hoon Koo, Dai Seg Bai; Yeungnam Univ J Med. 2010;27(1):27-36. Published online June 30, 2010; DOI: https://doi.org/10.12701/yujm.2010.27.1.27

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Abstract PDF

PURPOSE: The purpose of this study was to find out cognitive function of the patients with subjective memory complaint. MATERIAL AND METHODS: From March 1st 2005 to May 31st 2009, 155 normal individuals without any medical illness who visited Yeungnam University Hospital to undergo medical checkup with neurocognitive test was enrolled, and checked by using Cognitive Assessment & Reference Diagnostic System. RESULTS: 107 of the patients had normal cognitive function, 21 patients (about 15%) were diagnosed with dementia, and 10 patients (about 7%) were diagnosed with considerable psychiatric illness, such as depression, anxiety disorder, adjustment disorder. CONCLUSION: Because the patients with subjective memory complaint can be diagnosed as any psychiatric illness as well as dementia, sensitive screening test and early psychiatric approach is needed.

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Effects of a Cognition Activation Program for the Institutionalized Old-Old in Korea
Hung Sa Lee, Dohyun Lee
Journal of Korean Academy of Community Health Nursing.2013; 24(4): 427. CrossRef

Clinical Manifestation and Psychopharmacotherpy of Pediatric Bipolar Disorder: Wan Seok Seo; Yeungnam Univ J Med. 2007;24(2 Suppl):S252-261. Published online December 31, 2007; DOI: https://doi.org/10.12701/yujm.2007.24.2S.S252

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Abstract PDF: Pediatric bipolar disorder(BD) is one of the significant psychiatric health problems, which begins in childhood, has chronic persisting clinical course and leads impairs academic, occupational and legal problems of the patients. Fortunately, there has been increasing recognition of pediatric bipolar disorder during the past 10 years, even there are still controversy about clinical features and diagnosis. The clinical presentation of pediatric BD is greatly different to classic BD, relatively higher percentage of mixed, rapid cycling subtypes, not episodic and chronic lasting nature. In addition, pediatric BD has many comorbid psychiatric conditions such as attention deficit hyperactivity disorder, anxiety disorder and that makes more difficult to treat the patients with pediatric BD. To reduce confusion about diagnosis, the National Institute of Mental Health Research Roundtable divided pediatric BD into narrow and broad phenotype. 1) Given the paucity of medication trial studies of pediatric BD, no psychotrophic medications have been approved by U.S. Food and Drug Administration, except lithium. There have been a few open trials and retrospective chart reviews on the efficacy and side effects of mood stabilizers, anticonvulsants and atypical antipsychotics. More short and long-term randomized, double blind, well controlled trials of medication for pediatric BD are needed.

Risk Factors and Prevalence of Depression in the Patients of Schizophrenia: Jin-Sung Kim, Ji-Ann Ryu, Jong Bum Lee, Wan Seok Seo; Yeungnam Univ J Med. 2007;24(2 Suppl):S296-303. Published online December 31, 2007; DOI: https://doi.org/10.12701/yujm.2007.24.2S.S296

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Abstract PDF: Background
：This study performed to evaluate the patterns and prevalence of depression in patients with schizophrenia and to identify risk factors, using subjective and objective forms of depression scales. Materials and Methods：Demographic data and psychiatric history were obtained from the 139 participants with schizophrenia. The Beck Depression Inventory, Zung Self-Rating Depression Scale, Hamilton Rating Scale for Depression, and Calgary Depression Scale for Schizophrenia were applied to the participants to evaluate depression.
Results
：Thirty percent of all the participants had significant degree of depression, more in participants of outpatient unit and with earlier onset. Schizophrenic participants had more subjective feeling of depression than objective evaluation, performed by independent evaluators.
Conclusion
：Many schizophrenic patients have significant degree of depression. In treating schizophrenic patients, depression should be considered as an important target and variable of treatment.

Prognostic Factors in Postpsychotic Depressive Disorder of Schizophrenia.: Jin Sung Kim, Jong Bum Lee, Wan Seok Seo, Bon Hoon Koo, Yi Youg Kim, Jung Youp Kim; Yeungnam Univ J Med. 2005;22(2):150-165. Published online December 31, 2005; DOI: https://doi.org/10.12701/yujm.2005.22.2.150

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Abstract PDF: PURPOSE: This study was conducted to investigate the prognostic factors of postpsychotic depressive symptoms in patients with schizophrenia. MATERIALS AND METHODS: Eighty patients were selected based on the diagnostic criteria from the DSM-IV, PANSS and ESRS. For all patients information was collected on demographic and clinical characteristics. The subjective depressive symptoms and the objective depressive symptoms, as well as patients insight regarding psychosis were evaluated. The subjective depressive symptoms were evaluated by BDI and ZDS; the objective depressive symptoms were evaluated by HDRS and CDSS, and patient insight into the psychosis was evaluated by KISP. RESULTS: The comparisons using demographic and clinical characteristics showed that HDRS and CDSS had significant difference with regard to gender and suicide attempts; the BDI was associated with difference in education level and age of onset. The patients with scores above cuff-off score for each scale were 20 (25.0%) for the BDI, 16 (20.0%) for the ZDS, 18 (22.5%) for the CDSS and 6 (7.5%) for the HDRS. The results of the stepwise multiple regression analysis showed that the scores for the KISP, education levels, gender and suicide attempts were the main prognostic factors in patients with the psychotic depressive disorder of schizophrenia. CONCLUSION: The main prognostic factors in psychotic depressive disorder of schizophrenia included: insight into psychosis, suicidal attempts. Insight into the psychosis was the most reliable prognostic factor but this characteristic had a negative relationship to the with depressive symptoms.

The Relationship of Spiritual Well-being and Anxiety, Depression and Quality of Life in Active Old Age.: Hyong Uk Youm, Seung Deuk Cheung, Wan Seok Seo, Bon Hoon Koo, Dai Seg Bai; Yeungnam Univ J Med. 2005;22(1):27-42. Published online June 30, 2005; DOI: https://doi.org/10.12701/yujm.2005.22.1.27

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BACKGROUND
This study assessed the mental health, in order to determine the effect of the subject's spiritual well-being on anxiety depression and quality of life in active old people, and to verify whether or not spiritual well-being is a new factor for comprehensive health in old people. MATERIALS AND METHODS: This study selected 184 old people aged over 65 years. The subject's spiritual well-being was assessed by the Korean Spiritual Well-Being Scale (SWS) that was composed of the Religious Well-being Scale (RWS) and Existential Well-being Scale (EWS). The quality of life was assessed using Quality of Life Scale, which was composed of the subjective feeling about life and the subject's satisfaction of their whole life. RESULTS: Among the psychosocial factors, the educational level and physical health, showed significant discriminative score in the SWS. A prior medical history was associated with a significantly low SWS score. Satisfaction with life was associated with a significantly high SWS score. These factors a showed significant discriminative EWS score rather than a RWS. Among the religion factors, the satisfaction with their religion showed significant difference in the SWS. The SWS score especially the EWS affected the anxiety and depression of the Korean Combined Anxiety and Depression Scale (CADS). The subjective feeling of life score was associated with a significantly EWS low score and the subject's satisfaction with their whole life score was associated with a significantly high EWS score. CONCLUSION: Spiritual well being has significantly effects on anxiety depression and the quality of life in active old age people, and the subject; s spiritual well-being might be a new factor for assessing health in old age.

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Cultural involvement and attitudes toward tourism: Examining serial mediation effects of residents’ spiritual wellbeing and place attachment
Jieyi Li, Li Pan, Yaou Hu
Journal of Destination Marketing & Management.2021; 20: 100601. CrossRef
The Mediating Effect of Spirituality between Nurses' Empathy and Elderly Care Performance in the Long Term Care Hospitals
Heeok Park, Eun Kyung Kim, Kyoung Ja Moon, Min Ji Kim
Journal of Korean Academy of Community Health Nursing.2020; 31(1): 34. CrossRef
Effect of Death Education Program on Self-Esteem, Spiritual Well-Being, and Pain of Adults
Bock-Ryun Kim, Chung-uk Oh, Hye-kyung Kang
Journal of the Korea Academia-Industrial cooperation Society.2016; 17(9): 156. CrossRef
Factors Influencing Suicidal Ideation in Male Baby Boomers
Hee Sook Kim, Kwang Za Yu, Gyeong Ran Park
Journal of Korean Public Health Nursing.2014; 28(2): 347. CrossRef
Spiritual Well-Being, Social Support, Life Satisfaction and Depression in the Community Dwelling Elderly
So Nam Kim, Sang Bok Lee
journal of east-west nursing research.2013; 19(2): 186. CrossRef

The Effect of Spiritual Well-being on the Mental Health of the Cho-Sun Tribal Women Residing in P.R. of China.: Seung Deuk Cheung, Jong Bum Lee, Jin Sung Kim, Wan Seok Seo, Dai Seg Bai, Soon Jae Park, Yeol Joo, Hyoung Uk Youm, Cheung Yuan Jin, Jiu Miao Jin, Yeung Log Ahn, Da Hong Huang, Mei Zi Biao, Tai Ji Zheng, Chang Lie Zhao; Yeungnam Univ J Med. 2004;21(2):151-166. Published online December 31, 2004; DOI: https://doi.org/10.12701/yujm.2004.21.2.151

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BACKGROUND
Spirituality has been an important part of Transpersonal Psychology and is believed to have a large effect on the mental health because it has been systematized. The aim of this study was to determine the level of spiritual disposition on human beings along with its effects on one's mental health. MATERIALS AND METHODS: The study targeted 400 women residing in Youn-Gil city of JiLin Prov., which is a district of the Cho-Sun tribe in China. Their spiritual well-being was studied using the Spiritual Well-being Scale-Korean Version. The spiritual well-being scale consists of 2 sub-scales of religious well-being and existential well-being. The study was evaluated using a lie scale, psychotic trend, and a combined anxiety-depression scale. The results were considered to be factors of one's mental health. The correlation between the spiritual well-being and each tendency was analyzed by regression analysis. RESULTS: The total score of the Cho-Sun tribal women according to the spiritual well-being scale was 68.29 which was much less than the 100.65 of Korean Christian women. There was no significant correlation between the spiritual well-being and the Lie trend. However, it was found that 86% (344) of Cho-Sun tribal women scored above 70 in the Lie trend with a mean score of 74.57 which is higher than normal populations. Regarding the correlation between the spiritual well-being and psychotic trend, the psychotic trend became significantly higher when the religious well-being was at a high level. On the other hand, the psychotic trend became significantly lower when the existential well-being was at a high level. Regarding the correlation between the spiritual well-being and anxiety, the anxiety was significantly higher when the religious well-being was at a high level. However, the anxiety level was significantly low when the existential well-being was at a high level. Regarding the correlation between the spiritual well-being and depression, the depression level was somewhat significantly high when the religious well-being was at a high level. However, the depression level was significantly low when the existential well-being was at a high level. CONCLUSION: This study evaluated the effects of spiritual well-being on a person's mental health among Cho-Sun tribal women in Youn-Gil city of JiLIn Prov., P.R. of China. The results found that the religious well-being, which is a sub-scale of spiritual well-being, had negative effects while the existential well-being had positive effects on the mental health. These results proved that a person's religious disposition had negative effects on their mental health in a communitarian society.

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Spiritual Health in Korean Culture -Q methodological approach-
Hyung Wha Shim
Journal of Korean Academy of Fundamentals of Nursing.2015; 22(2): 129. CrossRef

The Comparison of Intelligence Efficacy According to Methylphenidate Administration in Attention Deficit Hyperactivity Disorder(ADHD) Patients.: Hyung Bae Park, Dae Seok Bai, Jeong Sang Ha, Wan Seok Seo, Chang Jin Song; Yeungnam Univ J Med. 2001;18(2):253-266. Published online December 31, 2001; DOI: https://doi.org/10.12701/yujm.2001.18.2.253

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Abstract PDF: BACKGROUND
The causes of ADHD(attention deficit hyperactivity disorder) are various, it is impossible to understand the whole characteristics of ADHD, only with simple intellignece testing scales. We compared cognitive characteristics of ADHD group with normal controls with Korean Kaufman Assessment Battery for Children(K-ABC), It is well known to evaluate neuropsychological and cognitive aspects of the children. MATERIALS AND METHODS: Age and sex matched 40 ADHD patients and 40 normal controls tested with the K-ABC. Each subscales compared between pre-treatment patients and controls, pre-treatment and post-treatment in patient group, post-treatment patients and controls. RESULTS: Significant differences are ovserved in sequential processing, simultaneous processing, cognitive processing and achievement between pre-treatment patients and controls, and in gestalt closure between pre-treatment and post-treatment patients group. But there are no significant differences between pre-treatment patients and controls in gestalt closure and reading/decoding. CONCLUSIONS: Methylphenidate improved the scores of simultaneous scale, which means improvement of executive functions such as divided attention, analysis and organization. Methylphenidate also reduced distractibility.

The Development of the Korean Form of Childhoood Attention Problem(CAP) Scale: A Study on the Reliability and Validity.: Wan Seok Seo, Jong Bum Lee, Hyung Bae Park, Hyea Soo Suh, Kwang Hun Lee, Jeong Kyn Sakong; Yeungnam Univ J Med. 1997;14(1):123-136. Published online June 30, 1997; DOI: https://doi.org/10.12701/yujm.1997.14.1.123

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Abstract PDF: The purpose of this study was to examine the reliability and validity of a Korean form of Childhood Attention Problem(CAP) scale. CAP were administered to 98 normal elementary school students as control group and 98 attention deficit hyperactivity disorder patients. Male students showed high scores than female students in both subscale and total scores, but not statistically significant. There were no significant difference in CAP scale between male students and female students in attention deficit hyperactivity disorder patients. In the reliability test, the test-retest reliability coefficient was highly satisfactory and that of inattention subscale was 0.83, impulsivity subscale was 0.70 and total score was 0.82. In the reliability test by internal consistency, the Cronbach a coefficient was highly satisfactory and that of inattention subscale was 0.91, overactivity subscale was 0.89(p<0.05). The concurrent validity between CAP scale and ADDES-HV scale was 0.85 in attention deficit hyperactivity disorder patient group and 0.73 in normal control group(p<0.05). In discriminant validity test between attention deficit hyperactivity disorder patient group and normal control group, the patient group showed higher score(p<0.05). The total discriminant capacity of the patient group in CAP was 93.4%. In this point of view, CAP scale showed high reliability and validity in applying to Korean subjects and was proved to be the good and simple screening test tool for attention deficit hyperactivity disorder research and can help many young patient to treat early.

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